Monday, April 29, 2013

Quotes

Misanthropic Quotes

“We have enslaved the rest of the animal creation, and have treated our distant cousins in fur and feathers so badly that beyond doubt, if they were able to formulate a religion, they would depict the devil in human form. ”-William Ralph Inge

“Man is an almost hopelessly conceited animal, this pygmy! He thinks that not only the earth with all that it contains was created for his benefit, but also the sky, the sun, and indeed, the whole universe, as far as he has any knowledge of it, were designed for his purposes and welfare.”- Ernest Bell

“I am ashamed of the race of beings to which I belong. It is so cruel and bigoted, so hypocritical, so soulless and insane. I would rather be an insect … a bee or a butterfly … and float in dim dreams among the wild-flowers of summer than be a man and feel the horrible and ghastly wrongs and sufferings of this wretched world.” – Professor J. Howard Moore

Positive Quotes

“Be soft. Do not let the world make you hard. Do not let pain make you hate. Do not let the bitterness steal your sweetness. Take pride that even though the rest of the world may disagree, you still believe it to be a beautiful place.”
- Kurt Vonnegut

“TO BE HOPEFUL in bad times is not just foolishly romantic. It is based on the fact that human history is a history not only of cruelty, but also of compassion, sacrifice, courage, kindness.
What we choose to emphasize in this complex history will determine our lives. If we see only the worst, it destroys our capacity to do something. If we remember those times and places—and there are so many—where people have behaved magnificently, this gives us the energy to act, and at least the possibility of sending this spinning top of a world in a different direction.
And if we do act, in however small a way, we don’t have to wait for some grand utopian future. The future is an infinite succession of presents, and to live now as we think human beings should live, in defiance of all that is bad around us, is itself a marvelous victory.”
- Howard Zinn

Monday, April 22, 2013

BP Gulf of Mexico Oil Spill 2010

The cover up: link

It's sad to think what all that toxic waste has done to the poor animals in the ocean - not just from a human perspective, but from their perspective.

Anti-biotic resistant bacteria in meat

link - We've known about it long enough. When are we going to look this problem in the face and take action. The best action is to stop eating meat!

Drug development - pieces of the puzzle


1) Drug development: Raise standards for preclinical cancer research

 http://www.nature.com/nature/journal/v483/n7391/full/483531a.html

2) Must try harder
http://www.nature.com/nature/journal/v483/n7391/full/483509a.html

It seems scientists are admitting that a lot of basic research on animals (preclinical studies) does not lead to benefits in clinical trials on humans (especially for cancer).  Many causes are suggested, lack of reproducibility, bad stats, publication bias, etc.  Only a few comments were made about the appropriateness of animal models.

From 1 above:
"Certainly, the limitations of preclinical tools such as inadequate cancer-cell-line and mouse models" (original source: Francia, G. & Kerbel, R. S. Nature Biotechnol. 28, 561562 (2010)). Note that animals are labelled as tools.


A commentator said: "The claims presented here are pretty outlandish. Particularly relevant to "Hematology and Oncology" we now know that mice housed under different conditions with different microflora can have vastly different outcomes in any model, not just cancer."